Version 5.4
Mus musculus Gene: Sox7
Summary
InnateDB Gene IDBG-173062.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox7
Gene Name SRY-box containing gene 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000063060
Encoded Proteins
IDBP-173064
SRY-box containing gene 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171056:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:63943674-63950732
Strand Forward strand
Band D1
Transcripts
ENSMUST00000079652 ENSMUSP00000078597
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0001706 endoderm formation
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008285 negative regulation of cell proliferation
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060828 regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171056
View Gene Order
ENSBTAG00000046258
Not yet available
Cross-References
SwissProt P40646
TrEMBL Q3U1W5
UniProt Splice Variant
Entrez Gene 20680
UniGene Mm.403389 Mm.42162
RefSeq NM_011446
OMIM
CCDS CCDS27206
HPRD
IMGT
MGI ID MGI:98369
MGI Symbol Sox7
EMBL AB023419 AK155670 BC131936 BC145925 CH466535 X65660
GenPept AAI31937 AAI45926 BAA78765 BAE33378 CAA46611 EDL36057
RNA Seq Atlas 20680

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca