Mus musculus Gene: Adamts5 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-173252.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Adamts5 | ||||||||||
Gene Name | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) | ||||||||||
Synonyms | 9530092O11Rik; ADAM-TS5; ADAMTS1; ADAMTS11; AI481094; ASMP-2 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000022894 | ||||||||||
Encoded Proteins |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154736:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 16:85858170-85901125 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | C3.3 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
O-glycosylation of TSR domain-containing proteins pathway
Extracellular matrix organization pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Post-translational protein modification pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9R001 | ||||||||||
TrEMBL | Q8BGP4 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 23794 | ||||||||||
UniGene | Mm.112933 Mm.456348 | ||||||||||
RefSeq | NM_011782 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS28288 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | MGI:1346321 | ||||||||||
MGI Symbol | Adamts5 | ||||||||||
EMBL | AF140673 AK044746 AK082475 BC138619 BC138620 | ||||||||||
GenPept | AAD56356 AAI38620 AAI38621 BAC32062 BAC38503 | ||||||||||
RNA Seq Atlas | 23794 | ||||||||||