Version 5.4
Mus musculus Gene: Senp8
Summary
InnateDB Gene IDBG-173389.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Senp8
Gene Name SUMO/sentrin specific peptidase 8
Synonyms 9130010J17Rik; AU020827; Den1; Nedp1; Prsc2
Species Mus musculus
Ensembl Gene ENSMUSG00000051705
Encoded Proteins
IDBP-173391
SUMO/sentrin specific peptidase 8
IDBP-627098
SUMO/sentrin specific peptidase 8
IDBP-742097
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166192:
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:59734259-59750649
Strand Reverse strand
Band B
Transcripts
ENSMUST00000051039 ENSMUSP00000054509
ENSMUST00000163586 ENSMUSP00000129441
ENSMUST00000177963 ENSMUSP00000137228
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
GO:0019784 NEDD8-specific protease activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000166192
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.279070 Mm.469182
RefSeq NM_001172068 NM_001172069 NM_001172070 NM_001172071 NM_027838
OMIM
CCDS CCDS23254 CCDS52819
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca