Version 5.4
Mus musculus Gene: Nrk
Summary
InnateDB Gene IDBG-173793.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrk
Gene Name Nik related kinase
Synonyms AA407323; AA409510; AI225895; AV168563; AW538185; Nesk
Species Mus musculus
Ensembl Gene ENSMUSG00000052854
Encoded Proteins
IDBP-173795
Nik related kinase
IDBP-254686
Nik related kinase
IDBP-542218
Nik related kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123572:
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:138914430-139010532
Strand Forward strand
Band F1
Transcripts
ENSMUST00000064937 ENSMUSP00000063397
ENSMUST00000113052 ENSMUSP00000108675
ENSMUST00000131829 ENSMUSP00000115962
ENSMUST00000142132
ENSMUST00000155201
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004702 receptor signaling protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005083 small GTPase regulator activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007256 activation of JNKK activity
GO:0007567 parturition
GO:0008285 negative regulation of cell proliferation
GO:0060721 regulation of spongiotrophoblast cell proliferation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123572
View Gene Order
ENSBTAG00000004836
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.482319
RefSeq NM_013724
OMIM
CCDS CCDS41143
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca