Mus musculus Gene: Skiv2l
Summary
InnateDB Gene IDBG-174107.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Skiv2l
Gene Name superkiller viralicidic activity 2-like (S. cerevisiae)
Synonyms 4930534J06Rik; AW214248; Ddx13; SKI; Ski2w
Species Mus musculus
Ensembl Gene ENSMUSG00000040356
Encoded Proteins
superkiller viralicidic activity 2-like (S. cerevisiae)
superkiller viralicidic activity 2-like (S. cerevisiae)
superkiller viralicidic activity 2-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204351:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:34839228-34850210
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000046022 ENSMUSP00000036265
ENSMUST00000174226
ENSMUST00000174887
ENSMUST00000174363
ENSMUST00000172803
ENSMUST00000173415 ENSMUSP00000134209
ENSMUST00000172878
ENSMUST00000173403
ENSMUST00000172686
ENSMUST00000173305
ENSMUST00000172966 ENSMUSP00000134294
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0055087 Ski complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
RNA degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Association of TriC/CCT with target proteins during biosynthesis pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
KEGG
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.18845
RefSeq NM_021337 XM_006523471 XM_006525267
OMIM
CCDS CCDS28661
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas