Version 5.4
Mus musculus Gene: Setmar
Summary
InnateDB Gene IDBG-174232.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Setmar
Gene Name SET domain and mariner transposase fusion gene
Synonyms 5830404F24Rik; Etet2
Species Mus musculus
Ensembl Gene ENSMUSG00000034639
Encoded Proteins
IDBP-174234
SET domain and mariner transposase fusion gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a histone-lysine N-methyltransferase that may be involved in the methylation of histone H3. In anthropoid primates this gene is a fusion gene of a SET histone-lysine N-methyltransferase and a mariner (MAR) family transposase. In all other species this gene contains only the SET domain. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:108065045-108077122
Strand Forward strand
Band E1
Transcripts
ENSMUST00000049246 ENSMUSP00000048225
ENSMUST00000138140
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0042803 protein homodimerization activity
GO:0043566 structure-specific DNA binding
Biological Process
GO:0000729 DNA double-strand break processing
GO:0000737 DNA catabolic process, endonucleolytic
GO:0034968 histone lysine methylation
GO:0071157 negative regulation of cell cycle arrest
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining
GO:2001251 negative regulation of chromosome organization
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000170364
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
mmu00310
Lysine degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt Q80UJ9
TrEMBL
UniProt Splice Variant
Entrez Gene 74729
UniGene Mm.407610 Mm.56539
RefSeq NM_178391
OMIM
CCDS CCDS51867
HPRD
IMGT
MGI ID MGI:1921979
MGI Symbol Setmar
EMBL AC153916 BC045208
GenPept AAH45208
RNA Seq Atlas 74729

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca