InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kif23

Summary

InnateDB Gene

IDBG-174424.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kif23

Gene Name

kinesin family member 23

Synonyms

3110001D19Rik; C87313; CHO1; Knsl5; MKLP-1; MKLP1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032254

Encoded Proteins

IDBP-174426

kinesin family member 23

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137807:
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:61917280-61946799

Strand

Reverse strand

Band

Transcripts

ENSMUST00000034815

ENSMUSP00000034815

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0000910	cytokinesis
GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0032467	positive regulation of cytokinesis
GO:0051256	spindle midzone assembly involved in mitosis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005819	spindle
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0030496	midbody
GO:0045171	intercellular bridge
GO:0072686	mitotic spindle
GO:0097149	centralspindlin complex