Version 5.4
Mus musculus Gene: Lphn3
Summary
InnateDB Gene IDBG-174445.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lphn3
Gene Name latrophilin 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037605
Encoded Proteins
IDBP-174447
latrophilin 3
IDBP-174449
latrophilin 3
IDBP-400728
latrophilin 3
IDBP-400726
latrophilin 3
IDBP-400729
latrophilin 3
IDBP-400727
latrophilin 3
IDBP-400730
latrophilin 3
IDBP-400725
latrophilin 3
IDBP-400724
latrophilin 3
IDBP-400723
latrophilin 3
IDBP-400722
latrophilin 3
IDBP-400719
latrophilin 3
IDBP-400716
latrophilin 3
IDBP-400713
latrophilin 3
IDBP-400721
latrophilin 3
IDBP-400717
latrophilin 3
IDBP-400715
latrophilin 3
IDBP-400714
latrophilin 3
IDBP-400712
latrophilin 3
IDBP-538951
latrophilin 3
IDBP-537246
latrophilin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150471:
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:81020138-81825133
Strand Forward strand
Band D
Transcripts
ENSMUST00000072521 ENSMUSP00000072336
ENSMUST00000036068 ENSMUSP00000045342
ENSMUST00000121707 ENSMUSP00000112823
ENSMUST00000120673 ENSMUSP00000113482
ENSMUST00000118034 ENSMUSP00000113534
ENSMUST00000121641 ENSMUSP00000113694
ENSMUST00000117985 ENSMUSP00000113950
ENSMUST00000122356 ENSMUSP00000113600
ENSMUST00000122037 ENSMUSP00000113374
ENSMUST00000119788 ENSMUSP00000114067
ENSMUST00000120128 ENSMUSP00000113208
ENSMUST00000118078 ENSMUSP00000112731
ENSMUST00000120144 ENSMUSP00000113619
ENSMUST00000120445 ENSMUSP00000113249
ENSMUST00000118442 ENSMUSP00000113836
ENSMUST00000120292 ENSMUSP00000112548
ENSMUST00000117407 ENSMUSP00000112388
ENSMUST00000119385 ENSMUSP00000113243
ENSMUST00000117253 ENSMUSP00000112470
ENSMUST00000147226
ENSMUST00000132375 ENSMUSP00000117211
ENSMUST00000149280
ENSMUST00000136104
ENSMUST00000148923
ENSMUST00000140356
ENSMUST00000132634
ENSMUST00000153264
ENSMUST00000127046
ENSMUST00000134597
ENSMUST00000126227
ENSMUST00000124117 ENSMUSP00000118882
ENSMUST00000148830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000150471
View Gene Order
ENSBTAG00000013918
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 319387
UniGene Mm.273631 Mm.407729
RefSeq NM_198702
OMIM
CCDS CCDS39122
HPRD
IMGT
MGI ID MGI:2441950
MGI Symbol Lphn3
EMBL
GenPept
RNA Seq Atlas 319387

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca