Version 5.4
Bos taurus Gene: LPHN3
Summary
InnateDB Gene IDBG-642614.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPHN3
Gene Name Latrophilin-3
Synonyms LEC3; LPHH3
Species Bos taurus
Ensembl Gene ENSBTAG00000013918
Encoded Proteins
IDBP-695107
Latrophilin-3
IDBP-695109
Latrophilin-3
IDBP-695110
Latrophilin-3
IDBP-695113
Latrophilin-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150471:
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:78991885-79313522
Strand Forward strand
Band
Transcripts
ENSBTAT00000039682 ENSBTAP00000039471
ENSBTAT00000018508 ENSBTAP00000018508
ENSBTAT00000051991 ENSBTAP00000049222
ENSBTAT00000066218 ENSBTAP00000055267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000150471
View Gene Order
ENSMUSG00000037605
View Gene Order
Cross-References
SwissProt
TrEMBL G3N0B0
UniProt Splice Variant
Entrez Gene 282651
UniGene Bt.13181
RefSeq XM_005208007 XM_005208008 NM_181033 XM_005208001 XM_005208002 XM_005208003 XM_005208004 XM_005208005 XM_005208010 XM_005208011 XM_005208012 XM_005208016
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017835 DAAA02017836 DAAA02017837 DAAA02017838 DAAA02017839 DAAA02017840
GenPept
RNA Seq Atlas 282651

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca