InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Neurl1a

Summary

InnateDB Gene

IDBG-174557.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Neurl1a

Gene Name

neuralized homolog 1A (Drosophila)

Synonyms

2410129E16Rik; AI450910; AI481072; Neu1; Neur1; Neurl; Neurl1; Nlz; Rnf67

Species

Mus musculus

Ensembl Gene

ENSMUSG00000006435

Encoded Proteins

IDBP-257343

neuralized homolog 1A (Drosophila)

IDBP-257345

neuralized homolog 1A (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107954:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:47178820-47259440

Strand

Forward strand

Band

Transcripts

ENSMUST00000111808	ENSMUSP00000107439
ENSMUST00000111807	ENSMUSP00000107438

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0045183	translation factor activity, non-nucleic acid binding

Biological Process

GO:0006417	regulation of translation
GO:0006513	protein monoubiquitination
GO:0007219	Notch signaling pathway
GO:0007288	sperm axoneme assembly
GO:0007420	brain development
GO:0007519	skeletal muscle tissue development
GO:0007595	lactation
GO:0008285	negative regulation of cell proliferation
GO:0030317	sperm motility
GO:0043065	positive regulation of apoptotic process
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity
GO:0045746	negative regulation of Notch signaling pathway
GO:0048170	positive regulation of long-term neuronal synaptic plasticity
GO:0051491	positive regulation of filopodium assembly
GO:0060999	positive regulation of dendritic spine development
GO:0071230	cellular response to amino acid stimulus
GO:0090129	positive regulation of synapse maturation

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0030054	cell junction
GO:0043197	dendritic spine
GO:0043204	perikaryon
GO:0045211	postsynaptic membrane
GO:0048471	perinuclear region of cytoplasm
GO:0097440	apical dendrite