Version 5.4
Mus musculus Gene: Dner
Summary
InnateDB Gene IDBG-174640.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dner
Gene Name delta/notch-like EGF-related receptor
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036766
Encoded Proteins
IDBP-174642
delta/notch-like EGF-related receptor
IDBP-788267
delta/notch-like EGF-related receptor
IDBP-788268
delta/notch-like EGF-related receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187957:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:84369839-84696221
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000049126 ENSMUSP00000042927
ENSMUST00000191306
ENSMUST00000185606 ENSMUSP00000140986
ENSMUST00000191546 ENSMUSP00000140662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0007220 Notch receptor processing
GO:0007417 central nervous system development
GO:0010001 glial cell differentiation
GO:0048741 skeletal muscle fiber development
Cellular Component
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187957
View Gene Order
ENSBTAG00000016063
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_199382
Signaling by NOTCH1 pathway
REACT_199384
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_199410
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_199405
Signaling by NOTCH1 in Cancer pathway
REACT_199407
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_199406
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_199409
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_199408
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118614
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
notch_pathway
Notch signaling pathway
Cross-References
SwissProt Q8JZM4
TrEMBL
UniProt Splice Variant
Entrez Gene 227325
UniGene Mm.292560 Mm.398085
RefSeq NM_152915
OMIM
CCDS CCDS15105
HPRD
IMGT
MGI ID MGI:2152889
MGI Symbol Dner
EMBL AB067650 AF370126 AK044597 AK152755 AK153235 AY032924 BC022636 BC034634
GenPept AAH22636 AAH34634 AAK50342 AAM14419 BAB72175 BAC31995 BAE31470 BAE31828
RNA Seq Atlas 227325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca