InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cenpc1

Summary

InnateDB Gene

IDBG-174876.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cenpc1

Gene Name

centromere protein C1

Synonyms

CENP-C; Cenpc

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029253

Encoded Proteins

IDBP-174878

centromere protein C1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145241:
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:86012043-86065583

Strand

Reverse strand

Band

Transcripts

ENSMUST00000031170

ENSMUSP00000031170

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019237	centromeric DNA binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0007059	chromosome segregation
GO:0007067	mitotic nuclear division
GO:0051382	kinetochore assembly

Cellular Component

GO:0000776	kinetochore
GO:0000777	condensed chromosome kinetochore
GO:0000780	condensed nuclear chromosome, centromeric region
GO:0005634	nucleus
GO:0005721	centromeric heterochromatin
GO:0005737	cytoplasm