InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col4a6

Summary

InnateDB Gene

IDBG-175155.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col4a6

Gene Name

collagen, type IV, alpha 6

Synonyms

BB116301

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031273

Encoded Proteins

IDBP-175159

collagen, type IV, alpha 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197565:
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:141165403-141474076

Strand

Reverse strand

Band

Transcripts

ENSMUST00000101205	ENSMUSP00000098765
ENSMUST00000137051
ENSMUST00000151459

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.