Version 5.4
Mus musculus Gene: Foxd2
Summary
InnateDB Gene IDBG-175582.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxd2
Gene Name forkhead box D2
Synonyms AI426778; Mf2
Species Mus musculus
Ensembl Gene ENSMUSG00000055210
Encoded Proteins
IDBP-175584
forkhead box D2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186564:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:114906282-114908873
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000068654 ENSMUSP00000066868
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001755 neural crest cell migration
GO:0001822 kidney development
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007389 pattern specification process
GO:0007422 peripheral nervous system development
GO:0030318 melanocyte differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048484 enteric nervous system development
GO:0048485 sympathetic nervous system development
GO:0048846 axon extension involved in axon guidance
GO:0048937 lateral line nerve glial cell development
GO:0050935 iridophore differentiation
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 cartilage development
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186564
View Gene Order
ENSBTAG00000045643
Not yet available
Cross-References
SwissProt O35392
TrEMBL
UniProt Splice Variant
Entrez Gene 17301
UniGene Mm.7997
RefSeq NM_008593
OMIM
CCDS CCDS18482
HPRD
IMGT
MGI ID MGI:1347471
MGI Symbol Foxd2
EMBL AF023915 AL670035
GenPept AAB81275 CAM19994
RNA Seq Atlas 17301

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca