Version 5.4
Mus musculus Gene: Sorcs3
Summary
InnateDB Gene IDBG-175842.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sorcs3
Gene Name sortilin-related VPS10 domain containing receptor 3
Synonyms 6330404A12Rik; AW045579
Species Mus musculus
Ensembl Gene ENSMUSG00000063434
Encoded Proteins
IDBP-175844
sortilin-related VPS10 domain containing receptor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156395:
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48206025-48805505
Strand Forward strand
Band D1
Transcripts
ENSMUST00000078880 ENSMUSP00000077919
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007612 learning
GO:0007613 memory
GO:1900452 regulation of long term synaptic depression
Cellular Component
GO:0016021 integral component of membrane
GO:0097481 neuronal postsynaptic density
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000156395
View Gene Order
Cross-References
SwissProt Q8VI51
TrEMBL Q1HL22
UniProt Splice Variant
Entrez Gene 66673
UniGene Mm.70980
RefSeq NM_025696
OMIM
CCDS CCDS38020
HPRD
IMGT
MGI ID MGI:1913923
MGI Symbol Sorcs3
EMBL AF276314 AK020713 DQ479928
GenPept AAL36983 ABF48507
RNA Seq Atlas 66673

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca