InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gucy2f

Summary

InnateDB Gene

IDBG-176018.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gucy2f

Gene Name

guanylate cyclase 2f

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000042282

Encoded Proteins

IDBP-176020

guanylate cyclase 2f

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101890:
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:142081160-142196931

Strand

Reverse strand

Band

Transcripts

ENSMUST00000042530

ENSMUSP00000044521

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004383	guanylate cyclase activity
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016849	phosphorus-oxygen lyase activity
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006182	cGMP biosynthetic process
GO:0006468	protein phosphorylation
GO:0007601	visual perception
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction