Mus musculus Gene: Spc25
Summary
InnateDB Gene IDBG-176021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spc25
Gene Name SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Synonyms 2600017H08Rik; 2610205L13Rik; Spbc25
Species Mus musculus
Ensembl Gene ENSMUSG00000005233
Encoded Proteins
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152253:
This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:69193895-69206194
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000005365 ENSMUSP00000005365
ENSMUST00000112320 ENSMUSP00000107939
ENSMUST00000127243 ENSMUSP00000120142
ENSMUST00000149045 ENSMUSP00000120999
ENSMUST00000149643 ENSMUSP00000117415
ENSMUST00000126638
ENSMUST00000149401
ENSMUST00000150505
ENSMUST00000167875 ENSMUSP00000128039
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007052 mitotic spindle organization
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0031262 Ndc80 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
M Phase pathway
Separation of Sister Chromatids pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Cell Cycle pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3UA16
TrEMBL A2AUT1 A2AUT3
UniProt Splice Variant
Entrez Gene 66442
UniGene Mm.272969 Mm.442767
RefSeq NM_001199123 NM_001199124 NM_025565
OMIM
CCDS CCDS57174 CCDS16088
HPRD
IMGT
MGI ID MGI:1913692
MGI Symbol Spc25
EMBL AK003408 AK011893 AK146727 AK151554 AL929221 BC027121 BC033605
GenPept AAH27121 AAH33605 BAB22772 BAB27900 BAE27390 BAE30499
RNA Seq Atlas 66442