Mus musculus Gene: Gemin5
Summary
InnateDB Gene IDBG-176086.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gemin5
Gene Name gem (nuclear organelle) associated protein 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037275
Encoded Proteins
gem (nuclear organelle) associated protein 5
gem (nuclear organelle) associated protein 5
gem (nuclear organelle) associated protein 5
gem (nuclear organelle) associated protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082516:
This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:58120002-58168539
Strand Reverse strand
Band B1.3
Transcripts
ENSMUST00000035604 ENSMUSP00000036603
ENSMUST00000102711 ENSMUSP00000099772
ENSMUST00000134733
ENSMUST00000134953 ENSMUSP00000116600
ENSMUST00000172035 ENSMUSP00000131842
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017069 snRNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0016604 nuclear body
GO:0032797 SMN complex
GO:0034719 SMN-Sm protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Metabolism of non-coding RNA pathway
snRNP Assembly pathway
Gene Expression pathway
KEGG
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
snRNP Assembly pathway
Metabolism of non-coding RNA pathway
Gene Expression pathway
KEGG
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275349 Mm.481282
RefSeq NM_001166669 NM_001166670 NM_001166671 NM_172558 XM_006532852 XM_006532853 XM_006537468 XM_006537469 XM_006537470
OMIM
CCDS CCDS24723 CCDS48802
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas