InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GEMIN5

Summary

InnateDB Gene

IDBG-646367.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GEMIN5

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012095

Encoded Proteins

IDBP-699169

gem (nuclear organelle) associated protein 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082516:
This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:68062402-68101734

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000016037

ENSBTAP00000016037

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017069	snRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0016604	nuclear body
GO:0032797	SMN complex
GO:0034719	SMN-Sm protein complex