Version 5.4
Mus musculus Gene: Xpnpep1
Summary
InnateDB Gene IDBG-176224.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpnpep1
Gene Name X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025027
Encoded Proteins
IDBP-789608
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
IDBP-789610
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
IDBP-789611
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
IDBP-789612
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108039:
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:52943417-53040214
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000183274 ENSMUSP00000138233
ENSMUST00000182500 ENSMUSP00000138097
ENSMUST00000182877
ENSMUST00000183108 ENSMUSP00000138250
ENSMUST00000182728
ENSMUST00000183188
ENSMUST00000182534
ENSMUST00000182844
ENSMUST00000182097 ENSMUSP00000138473
ENSMUST00000182887
ENSMUST00000182939
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
GO:0010815 bradykinin catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108039
View Gene Order
ENSBTAG00000004438
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_133216 XM_006526725
OMIM
CCDS CCDS29899
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca