Version 5.4
Mus musculus Gene: Sppl2b
Summary
InnateDB Gene IDBG-176307.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sppl2b
Gene Name signal peptide peptidase like 2B
Synonyms 3110056O03Rik; AW550292; PSL1
Species Mus musculus
Ensembl Gene ENSMUSG00000035206
Encoded Proteins
IDBP-176309
RIKEN cDNA 3110056O03 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:80855275-80868705
Strand Forward strand
Band C1
Transcripts
ENSMUST00000035597 ENSMUSP00000036289
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004190 aspartic-type endopeptidase activity
GO:0005515 protein binding
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
Biological Process
GO:0006509 membrane protein ectodomain proteolysis
GO:0031293 membrane protein intracellular domain proteolysis
GO:0050776 regulation of immune response
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q3TD49
TrEMBL Q8BXJ5
UniProt Splice Variant
Entrez Gene 73218
UniGene
RefSeq NM_175195 XM_006514209 XM_006514210 XM_006514212 XM_006514213 XM_006514215
OMIM
CCDS CCDS35988
HPRD
IMGT
MGI ID MGI:1920468
MGI Symbol Sppl2b
EMBL AK046804 AK148109 AK166364 AK170375 BC052094
GenPept AAH52094 BAC32878 BAE28349 BAE38734 BAE41755
RNA Seq Atlas 73218

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca