Version 5.4
Mus musculus Gene: Ambn
Summary
InnateDB Gene IDBG-177100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ambn
Gene Name ameloblastin
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029288
Encoded Proteins
IDBP-177102
ameloblastin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178522:
This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:88456011-88468527
Strand Forward strand
Band E1
Transcripts
ENSMUST00000031226 ENSMUSP00000031226
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0030021 extracellular matrix structural constituent conferring compression resistance
GO:0030345 structural constituent of tooth enamel
Biological Process
GO:0007155 cell adhesion
GO:0008283 cell proliferation
GO:0030198 extracellular matrix organization
GO:0031214 biomineral tissue development
GO:0042475 odontogenesis of dentin-containing tooth
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000178522
View Gene Order
ENSBTAG00000004793
Not yet available
Cross-References
SwissProt O55189
TrEMBL Q5M8P3
UniProt Splice Variant
Entrez Gene 11698
UniGene Mm.399779 Mm.8437
RefSeq NM_009664
OMIM
CCDS CCDS51539
HPRD
IMGT
MGI ID MGI:104655
MGI Symbol Ambn
EMBL BC087927 CH466617 U65021
GenPept AAB93765 AAH87927 EDL05362
RNA Seq Atlas 11698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca