Version 5.4
Mus musculus Protein: Ambn
Summary
InnateDB Protein IDBP-177102.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ambn
Protein Name ameloblastin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000031226
InnateDB Gene IDBG-177100 (Ambn)
Protein Structure
UniProt Annotation
Function Involved in the mineralization and structural organization of enamel.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity Ameloblast-specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0030021 extracellular matrix structural constituent conferring compression resistance
GO:0030345 structural constituent of tooth enamel
Biological Process
GO:0007155 cell adhesion
GO:0008283 cell proliferation
GO:0030198 extracellular matrix organization
GO:0031214 biomineral tissue development
GO:0042475 odontogenesis of dentin-containing tooth
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID MGI:104655
InterPro IPR007798 Ameloblastin precursor
PFAM PF05111
PRINTS
PIRSF
SMART SM00817
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O55189
PhosphoSite PhosphoSite-
TrEMBL Q5M8P3
UniProt Splice Variant
Entrez Gene 11698
UniGene Mm.8437
RefSeq NP_033794
MGI ID
MGI Symbol Ambn
OMIM
CCDS CCDS51539
HPRD
IMGT
EMBL BC087927 CH466617 U65021
GenPept AAB93765 AAH87927 EDL05362

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca