Version 5.4
Mus musculus Gene: Dnaja2
Summary
InnateDB Gene IDBG-177335.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnaja2
Gene Name DnaJ (Hsp40) homolog, subfamily A, member 2
Synonyms 1500017M13Rik; 2010206B19Rik; DNAJ; Dnaj3; DNJ3; HIRIP4; mDj3; PRO3015
Species Mus musculus
Ensembl Gene ENSMUSG00000031701
Encoded Proteins
IDBP-177337
DnaJ (Hsp40) homolog, subfamily A, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000069345:
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:85537640-85555271
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000034138 ENSMUSP00000034138
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031072 heat shock protein binding
GO:0046872 metal ion binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0009408 response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000069345
View Gene Order
ENSBTAG00000003757
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q9QYJ0
TrEMBL
UniProt Splice Variant
Entrez Gene 56445
UniGene Mm.279692 Mm.475573
RefSeq NM_019794
OMIM
CCDS CCDS22500
HPRD
IMGT
MGI ID MGI:1931882
MGI Symbol Dnaja2
EMBL AB028853 AK077672 AK083208 BC003420
GenPept AAH03420 BAA88301 BAC36946 BAC38809
RNA Seq Atlas 56445

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca