Version 5.4
Mus musculus Gene: Grsf1
Summary
InnateDB Gene IDBG-177457.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grsf1
Gene Name G-rich RNA sequence binding factor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000044221
Encoded Proteins
IDBP-177459
G-rich RNA sequence binding factor 1
IDBP-254325
G-rich RNA sequence binding factor 1
IDBP-541466
G-rich RNA sequence binding factor 1
IDBP-540260
G-rich RNA sequence binding factor 1
IDBP-540927
G-rich RNA sequence binding factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132463:
The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:88659448-88676171
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000078945 ENSMUSP00000077972
ENSMUST00000113234 ENSMUSP00000108860
ENSMUST00000130408
ENSMUST00000153565 ENSMUSP00000123051
ENSMUST00000133532 ENSMUSP00000114732
ENSMUST00000150438 ENSMUSP00000115589
ENSMUST00000137725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0009952 anterior/posterior pattern specification
GO:0016331 morphogenesis of embryonic epithelium
Cellular Component
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132463
View Gene Order
ENSBTAG00000008577
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_9491
Viral mRNA Translation pathway
REACT_6167
Influenza Infection pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_6145
Influenza Life Cycle pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.332474 Mm.472981
RefSeq NM_001098476 NM_178700
OMIM
CCDS CCDS19404 CCDS51540
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca