Version 5.4
Homo sapiens Gene: GRSF1
Summary
InnateDB Gene IDBG-22735.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRSF1
Gene Name G-rich RNA sequence binding factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132463
Encoded Proteins
IDBP-22737
G-rich RNA sequence binding factor 1
IDBP-484077
G-rich RNA sequence binding factor 1
IDBP-481143
G-rich RNA sequence binding factor 1
IDBP-483776
G-rich RNA sequence binding factor 1
IDBP-481496
G-rich RNA sequence binding factor 1
IDBP-599707
G-rich RNA sequence binding factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:70815782-70839945
Strand Reverse strand
Band q13.3
Transcripts
ENST00000254799 ENSP00000254799
ENST00000505068
ENST00000499044 ENSP00000427354
ENST00000502323 ENSP00000425430
ENST00000514161 ENSP00000421789
ENST00000506453 ENSP00000427644
ENST00000508091
ENST00000545193 ENSP00000443380
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
Experimentally validated
Total 50 [view]
Protein-Protein 50 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006378 mRNA polyadenylation
GO:0008033 tRNA processing
GO:0009952 anterior/posterior pattern specification
GO:0016331 morphogenesis of embryonic epithelium
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044221
View Gene Order
ENSBTAG00000008577
Not yet available
Pathways
NETPATH
REACTOME
REACT_9491
Viral mRNA Translation pathway
REACT_6167
Influenza Infection pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_6145
Influenza Life Cycle pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.309763 Hs.608894 Hs.629002 Hs.709934
RefSeq NM_001098477 NM_002092 XM_005265681 XM_005265685
HUGO
OMIM
CCDS CCDS47069 CCDS47070
HPRD 07276
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca