Version 5.4
Mus musculus Gene: Apba3
Summary
InnateDB Gene IDBG-177647.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Apba3
Gene Name amyloid beta (A4) precursor protein-binding, family A, member 3
Synonyms AW208791; lin-10; Mint-3; mint3; X11gamma
Species Mus musculus
Ensembl Gene ENSMUSG00000004931
Encoded Proteins
IDBP-177649
amyloid beta (A4) precursor protein-binding, family A, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011132:
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer\'s disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer\'s disease. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:81268172-81273246
Strand Forward strand
Band C1
Transcripts
ENSMUST00000057798 ENSMUSP00000050995
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001540 beta-amyloid binding
GO:0004857 enzyme inhibitor activity
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0001701 in utero embryonic development
GO:0007268 synaptic transmission
GO:0010468 regulation of gene expression
GO:0015031 protein transport
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000011132
View Gene Order
ENSBTAG00000008395
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.293931
RefSeq NM_018758 XM_006513905 XM_006513906
OMIM
CCDS CCDS24050
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca