Mus musculus Gene: Slc38a1
Summary
InnateDB Gene IDBG-178253.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc38a1
Gene Name solute carrier family 38, member 1
Synonyms AA408026; AA409865; AL022800; AU015942; NAT2
Species Mus musculus
Ensembl Gene ENSMUSG00000023169
Encoded Proteins
solute carrier family 38, member 1
solute carrier family 38, member 1
solute carrier family 38, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111371:
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:96571418-96642913
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000100262 ENSMUSP00000097833
ENSMUST00000088452 ENSMUSP00000085799
ENSMUST00000088454 ENSMUSP00000085801
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015186 L-glutamine transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006868 glutamine transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030424 axon
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Astrocytic Glutamate-Glutamine Uptake And Metabolism pathway
Neurotransmitter uptake and Metabolism In Glial Cells pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Amino acid transport across the plasma membrane pathway
Transmission across Chemical Synapses pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Amino acid transport across the plasma membrane pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Astrocytic Glutamate-Glutamine Uptake And Metabolism pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Neurotransmitter uptake and Metabolism In Glial Cells pathway
Transmission across Chemical Synapses pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.103568 Mm.407591 Mm.410047 Mm.430778
RefSeq NM_001166456 NM_001166458 NM_134086 XM_006520235
OMIM
CCDS CCDS27777
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas