Version 5.4
Mus musculus Gene: Hsd3b1
Summary
InnateDB Gene IDBG-178332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsd3b1
Gene Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms D3Ertd383e
Species Mus musculus
Ensembl Gene ENSMUSG00000027871
Encoded Proteins
IDBP-178334
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IDBP-267570
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IDBP-532316
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:98852194-98859794
Strand Reverse strand
Band F2.2
Transcripts
ENSMUST00000029465 ENSMUSP00000029465
ENSMUST00000107016 ENSMUSP00000102630
ENSMUST00000149768 ENSMUSP00000120119
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004769 steroid delta-isomerase activity
GO:0008831 dTDP-4-dehydrorhamnose reductase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_207160
Glucocorticoid biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_204887
Mineralocorticoid biosynthesis pathway
REACT_220332
Androgen biosynthesis pathway
REACT_220061
Metabolism of steroid hormones and vitamin D pathway
KEGG
mmu00140
Steroid hormone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2AEP7
UniProt Splice Variant
Entrez Gene 15492
UniGene Mm.140811 Mm.402306
RefSeq NM_008293 XM_006501035 XM_006501036 XM_006501037
OMIM
CCDS CCDS17670
HPRD
IMGT
MGI ID MGI:96233
MGI Symbol Hsd3b1
EMBL AL606755 AL671965
GenPept
RNA Seq Atlas 15492

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca