InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hsd3b1

Summary

InnateDB Protein

IDBP-532316.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hsd3b1

Protein Name

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

Synonyms

D3Ertd383e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120119

InnateDB Gene

IDBG-178332 (Hsd3b1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662	coenzyme binding

Biological Process

GO:0006694	steroid biosynthetic process
GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0044237	cellular metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:96233

InterPro

IPR001509 NAD-dependent epimerase/dehydratase
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR003869 Polysaccharide biosynthesis protein, CapD-like domain
IPR013120 Male sterility, NAD-binding

PFAM

PF01370
PF00106
PF01073
PF02719
PF07993

PRINTS

PR00080

PIRSF

PIRSF000126

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AEP7

UniProt Splice Variant

Entrez Gene

15492

UniGene

Mm.402306

RefSeq

MGI ID

MGI Symbol

Hsd3b1

OMIM

CCDS

HPRD

IMGT

EMBL

AL606755 AL671965

GenPept