Version 5.4
Mus musculus Gene: Dnahc11
Summary
InnateDB Gene IDBG-178380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnahc11
Gene Name dynein, axonemal, heavy chain 11
Synonyms b2b1203Clo; b2b1279Clo; b2b1289Clo; b2b1727Clo; b2b598Clo; Dnahc11; iv; lrd
Species Mus musculus
Ensembl Gene ENSMUSG00000018581
Encoded Proteins
IDBP-178382
dynein, axonemal, heavy chain 11
IDBP-711965
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105877:
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:117877982-118199043
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000084806 ENSMUSP00000081867
ENSMUST00000176756 ENSMUSP00000135748
ENSMUST00000175662
ENSMUST00000176239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0003341 cilium movement
GO:0006200 ATP catabolic process
GO:0007018 microtubule-based movement
GO:0007368 determination of left/right symmetry
Cellular Component
GO:0030286 dynein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105877
View Gene Order
ENSBTAG00000013078
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.390540
RefSeq NM_010060 XM_006515459 XM_006515460 XM_006515461 XM_006515462 XM_006515463 XM_006515464 XM_006515465 XM_006515466 XM_006515467 XM_006515468
OMIM
CCDS CCDS36578
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca