Version 5.4
Mus musculus Gene: Piwil2
Summary
InnateDB Gene IDBG-178442.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Piwil2
Gene Name piwi-like homolog 2 (Drosophila)
Synonyms mili; Piwil1l
Species Mus musculus
Ensembl Gene ENSMUSG00000033644
Encoded Proteins
IDBP-178444
piwi-like homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197181:
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70372480-70429094
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000048129 ENSMUSP00000047385
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0034584 piRNA binding
Biological Process
GO:0000966 RNA 5'-end processing
GO:0007126 meiotic nuclear division
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030718 germ-line stem cell maintenance
GO:0031047 gene silencing by RNA
GO:0034587 piRNA metabolic process
GO:0043046 DNA methylation involved in gamete generation
GO:0045727 positive regulation of translation
GO:0048477 oogenesis
GO:0060903 positive regulation of meiosis I
Cellular Component
GO:0005737 cytoplasm
GO:0005844 polysome
GO:0033391 chromatoid body
GO:0043186 P granule
GO:0071546 pi-body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197181
View Gene Order
ENSBTAG00000015835
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04320
Dorso-ventral axis formation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04320
Dorso-ventral axis formation pathway
INOH
PID NCI
Cross-References
SwissProt Q8CDG1
TrEMBL
UniProt Splice Variant
Entrez Gene 57746
UniGene Mm.85253
RefSeq NM_021308 XM_006519328 XM_006519329
OMIM
CCDS CCDS27252
HPRD
IMGT
MGI ID MGI:1930036
MGI Symbol Piwil2
EMBL AB032605 AF285586 AK030116 AK163647 BC138444 BC145717 CH466535
GenPept AAI38445 AAI45718 AAK31965 BAA93706 BAC26791 BAE37436 EDL35904
RNA Seq Atlas 57746

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca