Version 5.4
Mus musculus Gene: Cxcl3
Summary
InnateDB Gene IDBG-178846.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cxcl3
Gene Name chemokine (C-X-C motif) ligand 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029379
Encoded Proteins
IDBP-178848
chemokine (C-X-C motif) ligand 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:90786103-90788086
Strand Forward strand
Band E1
Transcripts
ENSMUST00000031326 ENSMUSP00000031326
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008009 chemokine activity
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0030593 neutrophil chemotaxis
GO:0032496 response to lipopolysaccharide
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04062
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q6W5C0
TrEMBL
UniProt Splice Variant
Entrez Gene 330122
UniGene Mm.471352
RefSeq NM_203320
OMIM
CCDS CCDS19417
HPRD
IMGT
MGI ID MGI:3037818
MGI Symbol Cxcl3
EMBL AK144158 AK150314 AK154334 AY311403 AY311404 BC117014 BC117016 CH466617
GenPept AAI17015 AAI17017 AAQ86936 AAQ86937 BAE25738 BAE29460 BAE32520 EDL05303
RNA Seq Atlas 330122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca