Version 5.4
Mus musculus Gene: Usp40
Summary
InnateDB Gene IDBG-178990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Usp40
Gene Name ubiquitin specific peptidase 40
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000005501
Encoded Proteins
IDBP-178992
ubiquitin specific peptidase 40
IDBP-789710
ubiquitin specific peptidase 40
IDBP-789711
ubiquitin specific peptidase 40
IDBP-789713
ubiquitin specific peptidase 40
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000085982:
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:87945119-88008551
Strand Reverse strand
Band D
Transcripts
ENSMUST00000040783 ENSMUSP00000038533
ENSMUST00000189409 ENSMUSP00000140240
ENSMUST00000187758 ENSMUSP00000140107
ENSMUST00000188332 ENSMUSP00000140574
ENSMUST00000186670
ENSMUST00000190446
ENSMUST00000186315
ENSMUST00000187871
ENSMUST00000189586
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000085982
View Gene Order
ENSBTAG00000000149
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 227334
UniGene
RefSeq NM_001033291 NM_001198573 XM_006529479 XM_006529480 XM_006529481
OMIM
CCDS CCDS15137
HPRD
IMGT
MGI ID MGI:2443184
MGI Symbol Usp40
EMBL
GenPept
RNA Seq Atlas 227334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca