Version 5.4
Mus musculus Gene: Srek1
Summary
InnateDB Gene IDBG-179315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srek1
Gene Name splicing regulatory glutamine/lysine-rich protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032621
Encoded Proteins
IDBP-179317
splicing regulatory glutamine/lysine-rich protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153914:
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:103741615-103764504
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000074616 ENSMUSP00000074196
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005739 mitochondrion
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000153914
View Gene Order
Cross-References
SwissProt Q8BZX4
TrEMBL
UniProt Splice Variant
Entrez Gene 218543
UniGene Mm.458176
RefSeq NM_172592 XM_006517607
OMIM
CCDS CCDS26743
HPRD
IMGT
MGI ID MGI:2145245
MGI Symbol Srek1
EMBL AK033354 AK037115 AK039311 AK044086 AK052265 BC070460
GenPept AAH70460 BAC28243 BAC29709 BAC30314 BAC31767 BAC34905
RNA Seq Atlas 218543

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca