Version 5.4
Mus musculus Gene: Ablim1
Summary
InnateDB Gene IDBG-179498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ablim1
Gene Name actin-binding LIM protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025085
Encoded Proteins
IDBP-179500
actin-binding LIM protein 1
IDBP-179502
actin-binding LIM protein 1
IDBP-257820
actin-binding LIM protein 1
IDBP-257822
actin-binding LIM protein 1
IDBP-257824
actin-binding LIM protein 1
IDBP-257826
actin-binding LIM protein 1
IDBP-257828
actin-binding LIM protein 1
IDBP-257830
actin-binding LIM protein 1
IDBP-257836
actin-binding LIM protein 1
IDBP-257838
actin-binding LIM protein 1
IDBP-257840
actin-binding LIM protein 1
IDBP-257842
actin-binding LIM protein 1
IDBP-622682
actin-binding LIM protein 1
IDBP-537966
actin-binding LIM protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099204:
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:57032733-57314919
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000099294 ENSMUSP00000096897
ENSMUST00000079360 ENSMUSP00000078336
ENSMUST00000111559 ENSMUSP00000107184
ENSMUST00000111558 ENSMUSP00000107183
ENSMUST00000111555 ENSMUSP00000107180
ENSMUST00000111550 ENSMUSP00000107175
ENSMUST00000111546 ENSMUSP00000107172
ENSMUST00000111544 ENSMUSP00000107169
ENSMUST00000111529 ENSMUSP00000107154
ENSMUST00000111528 ENSMUSP00000107153
ENSMUST00000111526 ENSMUSP00000107151
ENSMUST00000111524 ENSMUSP00000107149
ENSMUST00000104902 ENSMUSP00000127818
ENSMUST00000156316
ENSMUST00000137389
ENSMUST00000127198
ENSMUST00000133782
ENSMUST00000134430
ENSMUST00000150425
ENSMUST00000128212
ENSMUST00000133369 ENSMUSP00000117798
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007411 axon guidance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000099204
View Gene Order
ENSBTAG00000004899
Not yet available
Pathways
NETPATH
REACTOME
REACT_229826
Netrin-1 signaling pathway
REACT_248291
DCC mediated attractive signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22351
DCC mediated attractive signaling pathway
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.217161 Mm.365361 Mm.473413 Mm.487989
RefSeq NM_001103177 NM_001103178 NM_001290813 NM_001290815 NM_001290816 NM_178688 XM_006527028 XM_006527029 XM_006527030 XM_006527031 XM_006527032 XM_006527033 XM_006527042 XM_006527043 XM_006527045 XM_006527046 XM_006527047 XM_006527048
OMIM
CCDS CCDS38027 CCDS50478 CCDS50479 CCDS70963 CCDS70964
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca