Mus musculus Gene: Nt5m
Summary
InnateDB Gene IDBG-179584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nt5m
Gene Name 5',3'-nucleotidase, mitochondrial
Synonyms 2010013E09Rik; AI846937; dNT-2
Species Mus musculus
Ensembl Gene ENSMUSG00000032615
Encoded Proteins
5',3'-nucleotidase, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205309:
This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:59839447-59880968
Strand Forward strand
Band B1.3
Transcripts
ENSMUST00000102695 ENSMUSP00000099756
ENSMUST00000149076
ENSMUST00000154699
ENSMUST00000137695
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0008253 5'-nucleotidase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0016311 dephosphorylation
GO:0046079 dUMP catabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Pyrimidine metabolism pathway
Metabolism pathway
Pyrimidine catabolism pathway
Metabolism of nucleotides pathway
KEGG
Nicotinate and nicotinamide metabolism pathway
Pyrimidine metabolism pathway
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyrimidine catabolism pathway
Metabolism of nucleotides pathway
Pyrimidine metabolism pathway
Metabolism pathway
KEGG
Pyrimidine metabolism pathway
Nicotinate and nicotinamide metabolism pathway
Purine metabolism pathway
INOH
Nicotinate Nicotinamide metabolism pathway
Purine nucleotides nucleosides metabolism pathway
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.41761
RefSeq NM_134029
OMIM
CCDS CCDS24779
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas