Version 5.4
Mus musculus Gene: Ppef2
Summary
InnateDB Gene IDBG-179617.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppef2
Gene Name protein phosphatase, EF hand calcium-binding domain 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029410
Encoded Proteins
IDBP-179619
protein phosphatase, EF hand calcium-binding domain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156194:
This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:92226974-92253159
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000031359 ENSMUSP00000031359
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005506 iron ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0030544 Hsp70 protein binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0007601 visual perception
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0016311 dephosphorylation
GO:0043409 negative regulation of MAPK cascade
GO:0050906 detection of stimulus involved in sensory perception
Cellular Component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000156194
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.87155
RefSeq NM_011148 XM_006534817
OMIM
CCDS CCDS39151
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca