Mus musculus Gene: Ces1g
Summary
InnateDB Gene IDBG-180923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ces1g
Gene Name carboxylesterase 1G
Synonyms Ces-1; Ces1; Ses-1
Species Mus musculus
Ensembl Gene ENSMUSG00000057074
Encoded Proteins
carboxylesterase 1G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:93302369-93337308
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000044602 ENSMUSP00000037555
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8VCC2
TrEMBL Q3UW56
UniProt Splice Variant
Entrez Gene 12623
UniGene Mm.22720 Mm.400773
RefSeq NM_021456
OMIM
CCDS CCDS22531
HPRD
IMGT
MGI ID MGI:88378
MGI Symbol Ces1g
EMBL AK136446 AK136588 AK149446 AK162328 BC021150 BC026897 Y12887
GenPept AAH21150 AAH26897 BAE22982 BAE23063 BAE28882 BAE36856 CAA73388
RNA Seq Atlas 12623