InnateDB Gene
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IDBG-180923.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ces1g
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Gene Name
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carboxylesterase 1G
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Synonyms
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Ces-1; Ces1; Ses-1
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Species
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Mus musculus
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Ensembl Gene
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ENSMUSG00000057074
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Encoded Proteins
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Protein Structure
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Useful resources
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Stemformatics
EHFPI
ImmGen
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Summary |
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8. [provided by RefSeq, Jun 2010]
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Type |
Protein coding
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Genomic Location
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Chromosome 8:93302369-93337308
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Strand
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Reverse strand
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Band
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C5
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Transcripts
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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No orthologs found for this gene |
SwissProt
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Q8VCC2
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TrEMBL
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Q3UW56
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UniProt Splice Variant
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Entrez Gene
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12623
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UniGene
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Mm.22720
Mm.400773
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RefSeq
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NM_021456
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OMIM
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CCDS
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CCDS22531
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HPRD |
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IMGT
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MGI ID
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MGI:88378
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MGI Symbol
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Ces1g
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EMBL
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AK136446
AK136588
AK149446
AK162328
BC021150
BC026897
Y12887
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GenPept
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AAH21150
AAH26897
BAE22982
BAE23063
BAE28882
BAE36856
CAA73388
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RNA Seq Atlas
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12623
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