InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ces1g

Summary

InnateDB Protein

IDBP-180925.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ces1g

Protein Name

carboxylesterase 1G

Synonyms

Ces-1; Ces1; Ses-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037555

InnateDB Gene

IDBG-180923 (Ces1g)

Protein Structure

UniProt Annotation

Function

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. {ECO:0000269PubMed:9565681}.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000250}. Note=Microsomal membrane, lumen of endoplasmic reticulum. {ECO:0000250}.

Disease Associations

Tissue Specificity

Detected in kidney, liver and lung. {ECO:0000269PubMed:9565681}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016787	hydrolase activity
GO:0052689	carboxylic ester hydrolase activity

Biological Process

GO:0008152

metabolic process

Cellular Component

GO:0005788

endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

MGI:88378

InterPro

IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00135
PF07859

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VCC2

PhosphoSite

PhosphoSite-Q8VCC2

TrEMBL

Q3UW56

UniProt Splice Variant

Entrez Gene

12623

UniGene

Mm.400773

RefSeq

NP_067431

MGI ID

MGI Symbol

Ces1g

OMIM

CCDS

CCDS22531

HPRD

IMGT

EMBL

AK136446 AK136588 AK149446 AK162328 BC021150 BC026897 Y12887

GenPept

AAH21150 AAH26897 BAE22982 BAE23063 BAE28882 BAE36856 CAA73388