Version 5.4
Mus musculus Gene: Fkbp11
Summary
InnateDB Gene IDBG-180995.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fkbp11
Gene Name FK506 binding protein 11
Synonyms 1110002O23Rik; FKBP-11
Species Mus musculus
Ensembl Gene ENSMUSG00000003355
Encoded Proteins
IDBP-180997
FK506 binding protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134285:
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:98724373-98728198
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000003445 ENSMUSP00000003445
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0018208 peptidyl-proline modification
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134285
View Gene Order
ENSBTAG00000015828
Not yet available
Cross-References
SwissProt Q9D1M7
TrEMBL
UniProt Splice Variant
Entrez Gene 66120
UniGene Mm.401838
RefSeq NM_024169
OMIM
CCDS CCDS27803
HPRD
IMGT
MGI ID MGI:1913370
MGI Symbol Fkbp11
EMBL AK003331 AK019132 BC037596
GenPept AAH37596 BAB22719 BAB31559
RNA Seq Atlas 66120

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca