Version 5.4
Mus musculus Gene: Gpbp1
Summary
InnateDB Gene IDBG-182067.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpbp1
Gene Name GC-rich promoter binding protein 1
Synonyms 1700034P14Rik; AU019836; D230035M11Rik; Gpbp; mGPBP
Species Mus musculus
Ensembl Gene ENSMUSG00000032745
Encoded Proteins
IDBP-182069
GC-rich promoter binding protein 1
IDBP-182071
GC-rich promoter binding protein 1
IDBP-532381
GC-rich promoter binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000062194:
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:111425680-111490111
Strand Reverse strand
Band D2.2
Transcripts
ENSMUST00000047627 ENSMUSP00000048240
ENSMUST00000091236 ENSMUSP00000088777
ENSMUST00000136471 ENSMUSP00000123249
ENSMUST00000156221
ENSMUST00000143331
ENSMUST00000129638
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000062194
View Gene Order
ENSBTAG00000012124
Not yet available
Cross-References
SwissProt Q6NXH3
TrEMBL D6RCY3
UniProt Splice Variant
Entrez Gene 73274
UniGene Mm.399413 Mm.409347 Mm.57286
RefSeq NM_001122963 NM_028487 XM_006517772 XM_006517775
OMIM
CCDS CCDS26769 CCDS49362
HPRD
IMGT
MGI ID MGI:1920524
MGI Symbol Gpbp1
EMBL AC118475 AK082704 AK135728 AK145318 AK161928 AK163370 AK163390 AK169406 AY382529 BC016083 BC067075 BC094888
GenPept AAH16083 AAH67075 AAH94888 AAQ88446 BAC38578 BAE22631 BAE26364 BAE36638 BAE37320 BAE37330 BAE41152
RNA Seq Atlas 73274

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca