Version 5.4
Homo sapiens Gene: CLEC2A
Summary
InnateDB Gene IDBG-18208.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC2A
Gene Name C-type lectin domain family 2, member A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188393
Encoded Proteins
IDBP-18210
C-type lectin domain family 2, member A
IDBP-366750
C-type lectin domain family 2, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:9898673-9932381
Strand Reverse strand
Band p13.31
Transcripts
ENST00000339766 ENSP00000339732
ENST00000455827 ENSP00000396163
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0042267 natural killer cell mediated cytotoxicity
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q6UVW9
TrEMBL
UniProt Splice Variant
Entrez Gene 387836
UniGene Hs.527665
RefSeq NM_001130711 NM_207375 XM_005253366
HUGO HGNC:24191
OMIM 612087
CCDS CCDS44829 CCDS8606
HPRD
IMGT
EMBL AY359126 EF127467 EU095393 EU095394
GenPept AAQ89483 ABO33172 ABW79912 ABW79913
RNA Seq Atlas 387836

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca