Version 5.4
| Mus musculus Gene: Fgf5 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-182348.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Fgf5 | ||||||||||
| Gene Name | fibroblast growth factor 5 | ||||||||||
| Synonyms | angora; Fgf-5; go; HBGF-5 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000029337 | ||||||||||
| Encoded Proteins |
fibroblast growth factor 5
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene encodes a secreted protein that is a member of a family of heparin-binding growth factors. The encoded protein regulates cell proliferation, particularly the growth of hair follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 5:98254184-98277030 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | E3 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Innate Immune System pathway
FGFR3 ligand binding and activation pathway
Signaling by the B Cell Receptor (BCR) pathway
Signaling by ERBB2 pathway
PI3K/AKT activation pathway
Disease pathway
Signaling by Insulin receptor pathway
Signaling by FGFR in disease pathway
Signaling by ERBB4 pathway
Signaling by SCF-KIT pathway
PIP3 activates AKT signaling pathway
Immune System pathway
FGFR3c ligand binding and activation pathway
FGFR2 ligand binding and activation pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
Negative regulation of FGFR signaling pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
PI3K events in ERBB4 signaling pathway
PI-3K cascade pathway
FGFR ligand binding and activation pathway
Signaling by EGFR pathway
Insulin receptor signalling cascade pathway
IRS-related events triggered by IGF1R pathway
IGF1R signaling cascade pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
FGFR1c ligand binding and activation pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Phospholipase C-mediated cascade pathway
PI3K Cascade pathway
Signaling by FGFR2 mutants pathway
Activated point mutants of FGFR2 pathway
Signaling by activated point mutants of FGFR1 pathway
Fc epsilon receptor (FCERI) signaling pathway
PI3K/AKT Signaling in Cancer pathway
Signaling by FGFR mutants pathway
Signaling by FGFR1 mutants pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Signaling by PDGF pathway
FRS2-mediated cascade pathway
SHC-mediated cascade pathway
GAB1 signalosome pathway
IRS-related events pathway
NGF signalling via TRKA from the plasma membrane pathway
IRS-mediated signalling pathway
FGFR2c ligand binding and activation pathway
Signaling by FGFR3 mutants pathway
Signaling by activated point mutants of FGFR3 pathway
PI3K events in ERBB2 signaling pathway
Signal Transduction pathway
Signaling by FGFR pathway
Signaling by EGFR in Cancer pathway
FGFR1 ligand binding and activation pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
DAP12 interactions pathway
DAP12 signaling pathway
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| KEGG |
Melanoma pathway
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Pathways in cancer pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
DAP12 interactions pathway
Insulin receptor signalling cascade pathway
Signaling by FGFR1 mutants pathway
Signaling by EGFR pathway
GAB1 signalosome pathway
Negative regulation of FGFR signaling pathway
FGFR1 ligand binding and activation pathway
SHC-mediated cascade pathway
IRS-related events triggered by IGF1R pathway
Signaling by PDGF pathway
FGFR3c ligand binding and activation pathway
Signaling by ERBB4 pathway
FGFR ligand binding and activation pathway
Signaling by FGFR pathway
Signaling by FGFR mutants pathway
FGFR2 ligand binding and activation pathway
IRS-related events pathway
FGFR2c ligand binding and activation pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
FGFR3 ligand binding and activation pathway
PI3K events in ERBB2 signaling pathway
Immune System pathway
IRS-mediated signalling pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
IGF1R signaling cascade pathway
Signaling by the B Cell Receptor (BCR) pathway
Signaling by ERBB2 pathway
Signal Transduction pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
Signaling by EGFR in Cancer pathway
PI-3K cascade pathway
Signaling by FGFR3 mutants pathway
Signaling by activated point mutants of FGFR3 pathway
Activated point mutants of FGFR2 pathway
NGF signalling via TRKA from the plasma membrane pathway
PI3K events in ERBB4 signaling pathway
Downstream signaling of activated FGFR pathway
Signalling by NGF pathway
Signaling by activated point mutants of FGFR1 pathway
PI3K/AKT Signaling in Cancer pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Adaptive Immune System pathway
Phospholipase C-mediated cascade pathway
Downstream signal transduction pathway
PIP3 activates AKT signaling pathway
Signaling by SCF-KIT pathway
Innate Immune System pathway
PI3K/AKT activation pathway
FRS2-mediated cascade pathway
DAP12 signaling pathway
Disease pathway
Signaling by FGFR in disease pathway
Signaling by FGFR2 mutants pathway
Fc epsilon receptor (FCERI) signaling pathway
FGFR1c ligand binding and activation pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Melanoma pathway
Pathways in cancer pathway
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| INOH |
FGF signaling pathway pathway
GPCR signaling pathway
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| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | P15656 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 14176 | ||||||||||
| UniGene | Mm.5055 | ||||||||||
| RefSeq | NM_010203 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS19455 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:95519 | ||||||||||
| MGI Symbol | Fgf5 | ||||||||||
| EMBL | AB016516 AK028694 AK028894 BC071227 M30643 M37821 M37822 M37823 | ||||||||||
| GenPept | AAA96698 AAB02659 AAB02660 AAH71227 BAA33737 BAC26069 BAC26179 | ||||||||||
| RNA Seq Atlas | 14176 | ||||||||||