Version 5.4
Mus musculus Gene: H2-M3
Summary
InnateDB Gene IDBG-182403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-M3
Gene Name histocompatibility 2, M region locus 3
Synonyms H-2M3; Hmt; M3a; R4B2
Species Mus musculus
Ensembl Gene ENSMUSG00000016206
Encoded Proteins
IDBP-182405
histocompatibility 2, M region locus 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:37270220-37274484
Strand Forward strand
Band B1
Transcripts
ENSMUST00000038580 ENSMUSP00000035687
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002237 response to molecule of bacterial origin
GO:0002287 alpha-beta T cell activation involved in immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0006955 immune response
GO:0019882 antigen processing and presentation
GO:0032729 positive regulation of interferon-gamma production
GO:0042742 defense response to bacterium
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
Cellular Component
GO:0009897 external side of plasma membrane
GO:0032398 MHC class Ib protein complex
GO:0042612 MHC class I protein complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04940
Type I diabetes mellitus pathway
mmu04612
Antigen processing and presentation pathway
mmu05330
Allograft rejection pathway
mmu05332
Graft-versus-host disease pathway
mmu05320
Autoimmune thyroid disease pathway
mmu04144
Endocytosis pathway
mmu05416
Viral myocarditis pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q0WXH3 Q31093 Q7YP94 Q7YPD1 Q7YPG8
UniProt Splice Variant
Entrez Gene 14991
UniGene Mm.14437
RefSeq NM_013819
OMIM
CCDS CCDS37617
HPRD
IMGT
MGI ID MGI:95915
MGI Symbol H2-M3
EMBL AB267096 AY263512 AY263555 AY263595 CH466559 CT033782 U18797
GenPept AAA60335 AAP58754 AAP58791 AAP58828 BAF02294 EDL23336
RNA Seq Atlas 14991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca