InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Wnt5b

Summary

InnateDB Gene

IDBG-182694.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wnt5b

Gene Name

wingless-related MMTV integration site 5B

Synonyms

AW545702; Wnt-5b

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030170

Encoded Proteins

IDBP-400615

wingless-related MMTV integration site 5B

IDBP-400614

wingless-related MMTV integration site 5B

IDBP-400616

wingless-related MMTV integration site 5B

IDBP-715519

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111186:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:119432531-119544347

Strand

Reverse strand

Band

Transcripts

ENSMUST00000119369	ENSMUSP00000112448
ENSMUST00000117171	ENSMUSP00000113188
ENSMUST00000118120	ENSMUSP00000112819
ENSMUST00000178696	ENSMUSP00000137065

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005109	frizzled binding

Biological Process

GO:0002062	chondrocyte differentiation
GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0007275	multicellular organismal development
GO:0009887	organ morphogenesis
GO:0016055	Wnt signaling pathway
GO:0030182	neuron differentiation
GO:0030335	positive regulation of cell migration
GO:0042060	wound healing
GO:0045165	cell fate commitment
GO:0045600	positive regulation of fat cell differentiation
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005788	endoplasmic reticulum lumen
GO:0009986	cell surface
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome