Version 5.4
| Mus musculus Gene: Lhb | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-182968.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | Lhb | ||||||||||||||||||
| Gene Name | luteinizing hormone beta | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000038194 | ||||||||||||||||||
| Encoded Proteins |
luteinizing hormone beta
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104826:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | processed_transcript | ||||||||||||||||||
| Genomic Location | Chromosome 7:45418353-45421854 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | B3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
G alpha (s) signalling events pathway
Hormone ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Glycoprotein hormones pathway
Peptide hormone biosynthesis pathway
Mineralocorticoid biosynthesis pathway
Androgen biosynthesis pathway
Metabolism of lipids and lipoproteins pathway
Signaling by GPCR pathway
Metabolism of steroid hormones and vitamin D pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Metabolism of proteins pathway
GPCR ligand binding pathway
Metabolism pathway
Peptide hormone metabolism pathway
Peptide hormone metabolism pathway
Signaling by GPCR pathway
G alpha (s) signalling events pathway
Glycoprotein hormones pathway
Signal Transduction pathway
Peptide hormone biosynthesis pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
Mineralocorticoid biosynthesis pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Metabolism of steroid hormones and vitamin D pathway
Metabolism pathway
Class A/1 (Rhodopsin-like receptors) pathway
Hormone ligand-binding receptors pathway
Androgen biosynthesis pathway
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| KEGG |
GnRH signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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| INOH |
GPCR signaling pathway
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| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_008497 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS21242 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | |||||||||||||||||||
| MGI Symbol | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||