Mus musculus Gene: Dhdh
Summary
InnateDB Gene IDBG-183294.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhdh
Gene Name dihydrodiol dehydrogenase (dimeric)
Synonyms 1300018L09Rik; AA591799; Xld-1; Xld1
Species Mus musculus
Ensembl Gene ENSMUSG00000011382
Encoded Proteins
dihydrodiol dehydrogenase (dimeric)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104808:
This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45472956-45488805
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000011526 ENSMUSP00000011526
ENSMUST00000126050
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity
Biological Process
GO:0008152 metabolic process
GO:0042843 D-xylose catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Pentose and glucuronate interconversions pathway
Metabolism of xenobiotics by cytochrome P450 pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pentose and glucuronate interconversions pathway
Metabolism of xenobiotics by cytochrome P450 pathway
INOH
PID NCI
Cross-References
SwissProt Q9DBB8
TrEMBL
UniProt Splice Variant
Entrez Gene 71755
UniGene Mm.34208 Mm.415855 Mm.442859
RefSeq NM_027903
OMIM
CCDS CCDS21247
HPRD
IMGT
MGI ID MGI:1919005
MGI Symbol Dhdh
EMBL AK005050 AK154452 BC116414
GenPept AAI16415 BAB23776 BAE32596
RNA Seq Atlas 71755