Version 5.4
Mus musculus Gene: Aqp6
Summary
InnateDB Gene IDBG-183485.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp6
Gene Name aquaporin 6
Synonyms AI790337
Species Mus musculus
Ensembl Gene ENSMUSG00000043144
Encoded Proteins
IDBP-183487
aquaporin 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086159:
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:99601400-99605477
Strand Forward strand
Band F1
Transcripts
ENSMUST00000023754 ENSMUSP00000023754
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005253 anion channel activity
GO:0015112 nitrate transmembrane transporter activity
GO:0015250 water channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0015706 nitrate transport
GO:0042476 odontogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086159
View Gene Order
ENSBTAG00000012782
Not yet available
Pathways
NETPATH
REACTOME
REACT_226335
Aquaporin-mediated transport pathway
REACT_259079
Passive transport by Aquaporins pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23826
Passive transport by Aquaporins pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.202309
RefSeq NM_175087
OMIM
CCDS CCDS27824
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca