Version 5.4
Mus musculus Gene: Sycp3
Summary
InnateDB Gene IDBG-183499.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sycp3
Gene Name synaptonemal complex protein 3
Synonyms Cor1; Scp3
Species Mus musculus
Ensembl Gene ENSMUSG00000020059
Encoded Proteins
IDBP-183501
synaptonemal complex protein 3
IDBP-713018
IDBP-713459
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139351:
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:88459569-88473236
Strand Forward strand
Band C1
Transcripts
ENSMUST00000020252 ENSMUSP00000020252
ENSMUST00000123244 ENSMUSP00000137704
ENSMUST00000125612 ENSMUSP00000137800
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000711 meiotic DNA repair synthesis
GO:0007067 mitotic nuclear division
GO:0007126 meiotic nuclear division
GO:0007129 synapsis
GO:0007130 synaptonemal complex assembly
GO:0007283 spermatogenesis
GO:0035092 sperm chromatin condensation
GO:0051026 chiasma assembly
GO:0051878 lateral element assembly
Cellular Component
GO:0000793 condensed chromosome
GO:0000794 condensed nuclear chromosome
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0000802 transverse filament
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139351
View Gene Order
ENSBTAG00000002492
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.297977
RefSeq NM_011517
OMIM
CCDS CCDS24111
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca